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44 An international perspective on the use of aromatase inhibitors in breast cancer

โœ Scribed by C. Jackisch; S. Verma


Book ID
119601061
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
47 KB
Volume
8
Category
Article
ISSN
1359-6349

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Estrogens are the major hormones supporting the growth of human breast cancer. Aromatization of androgen precursors in peripheral tissues, including the breast cancer itself, is the major source of estrogens in postmenopausal women. Therefore, inhibition of the aromatase enzyme offers an effective m