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438 THE EXPRESSION OF P27 REDUCES DNA MUTAGENESIS AND CELL DEATH IN AFLATOXIN B1 INDUCED GENOTOXICITY IN HEPATOCYTES. IMPACT OF P27 AND P21 IN HUMAN HEPATOCARCINOGENESIS

✍ Scribed by I. Ranchal; A. Poyato; P. Barrera; M. Pleguezuelo; T. Marchal; K.I. Nakayama; M. De la Mata; J. Muntane


Book ID
117376364
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
63 KB
Volume
48
Category
Article
ISSN
0168-8278

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## Abstract Hepatocellular carcinoma (HCC) is the fifth most commonly occurring cancer worldwide. The expression of p27 has been related to reduced severity of tumor grade and recurrence of HCC. The study assessed the role of p27 on the cell proliferation and death, and DNA mutagenesis in experimen