Formation of pentafluorophenyldimethylsi
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E.D. Morgan; C.F. Poole
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Article
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1975
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Elsevier Science
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English
β 675 KB
The pentafluorophenyldimethylsilyl group is an excellent protecting group for steroid alcohols, giving volatile ethers, detectable at picogram levels in gas chromatography with an electron capture detector. By the use of five reagents, increasingly hindered hydroxyl groups can be protected, so that