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433 The effect of nedocromil sodium on the bronchoconstrictor effect of neurokinin a in asthmatics

โœ Scribed by JOOS, G; PAUWELS, R; VANDERSTRAETEN, M

Book ID
119059118
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
135 KB
Volume
81
Category
Article
ISSN
1097-6825

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Leukotriene D4 (LTD4) is a potent bronchoconstrictor and vasoactive mediator that has been implicated in the pathogenesis of bronchial asthma. We have studied the effect of SK&F 104353-Z2, a specific LTD4 antagonist, on LTD4-induced bronchoconstriction in asthmatics. A total of 12 mild asthmatics (m