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428 THE OSTEOBLASTIC RESPONSE BY PROSTATE CANCER BONE METASTASES IS DETERMINED BY THE LACK OF EXPRESSION OF NOGGIN AND DICKKOPF-1 (DKK-1)

✍ Scribed by C.A. Rentsch; R. Schwaninger; A. Wetterwald; G. Van Der Horst; R.L. Van Bezooijen; G. Van Der Pluijm; C.W.G.M. Loewik; K. Ackermann; W. Pyerin; F.C. Hamdy; G.N. Thalmann; M.G. Cecchini


Book ID
119617759
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
356 KB
Volume
6
Category
Article
ISSN
1569-9056

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## Abstract Head and neck cancers are treated by a combination of surgery, radiotherapy and/or chemotherapy. The clinical success of cisplatin‐based chemotherapy, mostly in combination with 5‐FU or a taxane, is however limited by multifactorial intrinsic or acquired resistance. So far, known genes