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413 Impact of CD1d+CD5+ B-Cells on T-Dependent and T-Independent Immune Responses in Early Childhood

✍ Scribed by Y. Ling; E. Dijke; L.J. West; S. Urschel


Book ID
116524068
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
120 KB
Volume
31
Category
Article
ISSN
1557-3117

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This study tracks the fate of antigen-reactive B cells through follicular and extrafollicular responses and addresses the function of CD40 in these processes. The unique feature of this system is the use of transgenic B cells in which the heavy chain locus has been altered by site-directed insertion