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412 Inhibition of Phosphatidylcholine-specific Phospholipase C Interferes With Proliferation and Survival of Tumor Initiating Cells

✍ Scribed by B. Ileana; S. Cecchetti; E. Iorio; S. Miotti; F. Podo; S. Canevari


Book ID
117662931
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
56 KB
Volume
48
Category
Article
ISSN
0959-8049

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CHANGES OF PHOSPHATIDYLCHOLINE-SPECIFIC
✍ WU XINGZHONG; HONG LU; LAN ZHOU; YONG HUANG; HUILI CHEN πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 English βš– 171 KB

The biological significance of phosphatidylcholine-specific phospholipase C (PC-PLC) in hepatocarcinogenesis and the proliferation and differentiation of rat liver cancer cells was investigated. The Ca 2+ -dependent activities of PC-PLC gradually increased during N-nitrosodiethylamine (DEN)-induced