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411 LONGITUDINAL CHANGES IN THE SPATIAL DISTRIBUTION OF CARTILAGE MR T2 IN A SUBSET OF PATIENTS FROM THE OSTEOARTHRITIS INITIATIVE

✍ Scribed by G. Blumenkrantz; J. Carballido-Gamio; B. Hyun; J.A. Lynch; T.M. Link; S. Majumdar


Book ID
114351038
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
149 KB
Volume
16
Category
Article
ISSN
1063-4584

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## Abstract The purpose of this pilot study was to longitudinally quantify the __T__~2~ laminar integrity of knee cartilage in a subset of subjects with osteoarthritis from the Osteoarthritis Initiative at baseline, 1‐year follow‐up, and 2‐year follow‐up. Cartilage from 13 subjects was divided into

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Cartilage magnetic resonance imaging T 2 relaxation time is sensitive to hydration, collagen content, and tissue anisotropy, and a potential imaging-based biomarker for knee osteoarthritis. This longitudinal pilot study presents an improved cartilage flattening technique that facilitates texture ana