𝔖 Bobbio Scriptorium
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411 Enhancement of binding of tissue plasminogen activator to fibrin in the presence of ultrasound

Book ID
114201534
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
148 KB
Volume
10
Category
Article
ISSN
0268-9499

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Molecular assembly of plasminogen and tissue-type plasminogen actwator (t-PA) at the surface of fibrin results in the generation of fibrin-bound plasmin and thereby in the dissolution of a clot. This mechanism is triggered by specific interactions of intra-chain surface lysine residues in fibrin wit