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4103 Phase I study of temozolomide combined with oral etoposide in children with recurrent or progressive medulloblastoma

✍ Scribed by A. Ruggiero; D. Rizzo; G. Attinà; I. Lazzareschi; P. Maurizi; S. Mastrangelo; R. Migliorati; P. Bertolini; M. Pastore; R. Riccardi

Book ID
119600514
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
48 KB
Volume
7
Category
Article
ISSN
1359-6349

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✍ David N. Korones; Michal Benita-Weiss; Thomas E. Coyle; Laszlo Mechtler; Peter B 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 74 KB

## Abstract ## BACKGROUND Although temozolomide is active against recurrent malignant glioma, responses in many patients are modest and short‐lived. Temozolomide may prove more effective in combination with other agents. Therefore, combination oral chemotherapy for these patients is a particularly