𝔖 Bobbio Scriptorium
✦   LIBER   ✦

408 New sequence variants, recurrent BRCA1/BRCA2 mutations and new aberrations in BRCA1 promoter region in breast and ovarian cancer cases from upper silesia in Poland

✍ Scribed by J. Pamula; H. Zientek; M. Sieminska; W. Pekala; E. Chmielik; J. Rogozinska-Szczepka; B. Utracka-Hutka; M. Rusin; E. Grzybowska

Book ID
118620582
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
340 KB
Volume
1
Category
Article
ISSN
1359-6349

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

BRCA1 and BRCA2 mutation analysis in bre
BRCA1 and BRCA2 mutation analysis in breast-ovarian cancer families from northeastern Poland
✍ Magdalena Perkowska; Izabela BroΕ»ek; Barbara Wysocka; Karin Haraldsson; Therese πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 66 KB πŸ‘ 2 views

Sixty high-risk breast and/or ovarian cancer families from North-Eastern Poland were screened for germline mutations in BRCA1 (MIM# 113705) and BRCA2 (MIM# 600185), using a combination of protein truncation test, denaturing high-performance liquid chromatography and direct sequencing. Sixteen (27%)

Founder BRCA1 mutations and two novel ge
Founder BRCA1 mutations and two novel germline BRCA2 mutations in breast and/or ovarian cancer families from North-Eastern Poland
✍ Marco van der Looij; Barbara Wysocka; Izabela Brozek; Jacek Jassem; Janusz Limon πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 30 KB πŸ‘ 3 views

Germline mutations in the BRCA1 and BRCA2 genes account for the majority of high-risk breast/ovarian cancer families, depending on the population studied. Previously, BRCA1 mutations were described in women from Western Poland. To further characterize the spectrum of BRCA1 mutations and the impact o