Effect of tumor-associated mutant E-cadh
✍
Margit Fuchs; Christine Hermannstädter; Katja Specht; Pjotr Knyazev; Axel Ullric
📂
Article
📅
2004
🏛
John Wiley and Sons
🌐
English
⚖ 285 KB
## Abstract Tumor progression is characterized by loss of cell adhesion and increase of invasion and metastasis. The cell adhesion molecule E‐cadherin is frequently down‐regulated or mutated in tumors. In addition to down‐regulation of cell adhesion, degradation of the extracellular matrix by matri