402 POSTER A phase I study of gemcitabine, capecitabine and vandetanib in patients with advanced solid tumors with an expanded cohort in biliary and pancreatic malignancies
β Scribed by S. Leong; C.L. Obryant; W.A. Messersmith; S. Diab; M.A. Kane; S. Nallapreddy; C. Weekes; J. Spratlin; J. Call; S.G. Eckhardt
- Book ID
- 119599558
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 58 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1359-6349
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A Phase I study was initiated to determine the maximum tolerated dose of weekly gemcitabine combined with monthly, fixed-dose docetaxel. ## METHODS. Patients with metastatic solid tumors were treated with docetaxel, 60 mg/m 2 , on Day 1 every 28 days. Gemcitabine was administered on Days 1, 8, and
## Abstract ## BACKGROUND Pegylated liposomal doxorubicin (PEGβLD) and gemcitabine have singleβagent activity in breast and ovarian carcinoma patients. We conducted a Phase I trial to evaluate the maximum tolerated dose (MTD) and toxicities of this combination in patients with advanced malignancie