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4-(β-Arylvinyl)-3-(β-arylvinylketo)-1-ethyl-4-piperidinols and Related Compounds: A Novel Class of Cytotoxic and Anticancer Agents

✍ Scribed by Dimmock, Jonathan R.; Vashishtha, Sarvesh C.; Quail, J. Wilson; Pugazhenthi, Uma; Zimpel, Zbigniew; Sudom, Athena M.; Allen, Theresa M.; Kao, Grace Y.; Balzarini, Jan; De Clercq, Erik


Book ID
127308624
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
134 KB
Volume
41
Category
Article
ISSN
0022-2623

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✍ V. Alagarsamy; P. Parthiban; V. Raja Solomon; K. Dhanabal; S. Murugesan; G. Sara 📂 Article 📅 2008 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 312 KB

## Abstract magnified image A series of novel 4‐(4‐ethylphenyl)‐1‐substituted‐4__H__‐[1,2,4]triazolo[4,3‐__a__]quinazolin‐5‐ones were synthesized by the cyclization of 2‐hydrazino intermediate with various electrophile. The starting material 2‐hydrazino compound was synthesized from 2‐ethyl anilin