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4-Substituted-5(3)-carbamoyl-3(5)-(2-deoxy-β- D -ribofuranosyl)pyrazoles. Application of Palladium Catalyzed Glycal Coupling Methodology to the Synthesis of Pyrazofurin Analogs

✍ Scribed by Erion, Mark D.; Rydzewski†, Robert M.

Book ID: 121473966
Publisher: Taylor and Francis Group
Year: 1997
Tongue: English
Weight: 932 KB
Volume: 16
Category: Article
ISSN: 0732-8311
DOI: 10.1080/07328319708001352

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ChemInform Abstract: 4-Substituted-5(3)-

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✍ M. D. ERION; R. M. RYDZEWSKI 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 1 views

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A series of 6-substituted purine nucleosides have been synthesized in mcderate yield by the nickel catalyzed cross coupling reaction between alkyl-and aryl-Griqnard reagents and 2',3',5'-tris-@-(t-butyldimethylsilyl)-9-~-~-ribofuranosy1-6-chloropurine. Adenosine analogues with alkyl and aryl group l