4-Methyl-1,2,5,6-tetrahydrobenzo[f]quinolin-3(4H)-one. The Cyclization Product Derived from Methyl 3-[(3,4-Dihydro-2-naphthyl)methyl-amino]propionate
✍ Scribed by Horii, Zen-Ichi; Iwata, Chuzo; Tamura, Yasumitsu; Nelson, Norman A.; Rasmusson, Gary H.
- Book ID
- 126997882
- Publisher
- American Chemical Society
- Year
- 1964
- Tongue
- English
- Weight
- 296 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0022-3263
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📜 SIMILAR VOLUMES
The title compound, C~11~H~13~N~3~O, is a key intermediate in the synthesis of cardiotonic agents. The asymmetric unit consists of two molecules of the same enantiomer and the crystal packing is stabilized by intermolecular N—H...O hydrogen bonds.
In an extension of our studies on the thermal decomposition of Amadori compounds (l), we have identified 2,3-dihydro-3,5-dihydroxy-6-methyl-4&pyran-4-one (Ia) as the major solid product that is volatilized during the pyrolysis of l-deoxy-l-(k-prolino)-&fructose at 138"/1 mm. The structural assignmen