4 L-735, 524: An orally bioavailable human immunodeficiency virus type 1 protease inhibitor: E.A. Emini, J.P. Vacca, B.D. Dorsey, W.A. Schleif, R.B. Levin, S.L. McDaniel, P.L. Darke, J.A. Zugay, J.C. Quintero, O.M. Blahy, E. Roth, V.V. Sardana, A.J. Schlabach, J.H. Condra, L. Gotlib, K. Holloway, J. Lin, J.-W. Chen, D. Ostovic, P.S. Anderson and J.R. Huff. Merck Research Laboratories, West Point, PA 19486 USA. Bristol Myers Squibb Pharmaceutical Research Institute P.P. Box 4000, Princeton, New Jersey 08543 USA †5 Research Parkway Wallingford, Connecticut, 06492, USA