✦ LIBER ✦

4-Hydroxytamoxifen binds to estrogen receptors and inhibits the growth of human endometrial cancer cells in vitro

✍ Scribed by Naoki Terakawa; Ikuya Shimizu; Hiromasa Ikegami; Osamu Tanizawa; Keishi Matsumoto

Publisher: John Wiley and Sons
Year: 1988
Tongue: English
Weight: 457 KB
Volume: 61
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(19880401)61:7<1312::aid-cncr2820610706>3.0.co;2-k

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Amphiregulin antisense oligonucleotide i

Amphiregulin antisense oligonucleotide inhibits the growth of T3M4 human pancreatic cancer cells and sensitizes the cells to EGF receptor-targeted therapy

✍ Hitoshi Funatomi; Jun Itakura; Toshiyuki Ishiwata; Ira Pastan; Stewart A. Thomps 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 152 KB 👁 2 views

Human pancreatic cancers overexpress the epidermal growth factor (EGF) receptor (EGFR) and all 5 ligands that bind to this receptor, including amphiregulin. It is not known, however, whether amphiregulin contributes in an autocrine manner to enhance pancreatic cancer cell growth. Therefore, we used

Comparative binding affinities of tamoxi

Comparative binding affinities of tamoxifen, 4-hydroxytamoxifen, and desmethyltamoxifen for estrogen receptors isolated from human breast carcinoma: Correlation with blood levels in patients with metastatic breast cancer

✍ Carol Fabian; Lowell Tilzer; Larry Sternson 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 English ⚖ 470 KB 👁 1 views

## Abstract The relative ability of the antiestrogen, tamoxifen, and its monohydroxy and desmethyl metabolites to displace tritiated estradiol from estrogen receptors isolated from human breast carcinoma was determined. 4‐Hydroxytamoxifen binds to the estrogen receptor with affinity equal to estrad

Recombinant antibody toxins specific for

Recombinant antibody toxins specific for ErbB2 and EGF receptor inhibit the in vitro growth of human head and neck cancer cells and cause rapid tumor regression in vivo

✍ Marc Azemar; Mathias Schmidt; Friederike Arlt; Pierre Kennel; Burkhard Brandt; A 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 130 KB 👁 2 views

## Overexpression of the ErbB2 and epidermal growth factor receptor (EGFR) tyrosine kinases is frequently observed in squamous cell carcinomas of the head and neck, and has been correlated with shorter overall survival. By immunoblot analysis, we have found EGFR and ErbB2 expression in 6 out of 6 e