4. Effects of DNA methylation on hepatitis B virus (HBV) transcription and binding of CREB and CREB-like proteins to the HBV promoter
β Scribed by Nicholson, R; Chen, L; Christman, JK
- Book ID
- 123529093
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 130 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0753-3322
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Hepatitis B markers were studied in seven patients with reactivated liver disease. Reactivation of chronic type B hepatitis, as indicated by the reappearance of hepatitis B e antigen (HBeAg) in the serum, was characterised by the appearance of hepatitis B virus-DNA (HBV-DNA) in the serum. The expres
## Abstract DNA is exposed to endogenous and environmental factors that can form stable lesions. If not repaired, these lesions can lead to transcription/replication blocking or mutagenic bypass. Our previous work has focused on 8,5β²βcyclopurine 2β²βdeoxyribonucleosides, a unique class of oxidativel