The crystal structure of commercially available 4-hydroxyphenylacetic acid, C 8 H 8 O 3 , is non-centrosymmetric, with four hydrogen bonds between each molecule and adjacent molecules. The hydrogen bonds link the molecules in the crystal structure into an infinite three-dimensional framework.
4-Aminophenylacetic acid
✍ Scribed by Gracin, Sandra ;Svärd, Michael ;Fischer, Andreas
- Publisher
- International Union of Crystallography
- Year
- 2005
- Tongue
- English
- Weight
- 136 KB
- Volume
- 61
- Category
- Article
- ISSN
- 1600-5368
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✦ Synopsis
Crystals of the title compound, C 8 H 9 NO 2 , were obtained from ethyl acetate. The structure consists of the acid in its zwitterionic form. In the crystal structure, each molecule interacts through strong N-HÁ Á ÁO hydrogen bonds with six adjacent molecules, yielding a three-dimensional network.
📜 SIMILAR VOLUMES
Single-crystal X-ray study T = 293 K Mean '(C±C) = 0.002 A Ê R factor = 0.041 wR factor = 0.109 Data-to-parameter ratio = 12.5 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.
## Abstract Phenylacetic acid mustard (PAM; **2**), a major metabolite of the anticancer agent chlorambucil (CLB; **1**), was allowed to react with 2′‐deoxyadenosine (dA), 2′‐deoxyguanosine (dG), 2′‐deoxycytidine (dC), 2′‐deoxy‐5‐methylcytidine (dMeC), and thymidine (T) at physiological pH (cacodyl
Single-crystal X-ray study T = 293 K Mean '(C±C) = 0.003 A Ê R factor = 0.063 wR factor = 0.225 Data-to-parameter ratio = 14.3 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.