4-Acylamino-and 4-ureidobenzamides as melanin-concentrating hormone (MCH) receptor 1 antagonists
✍ Scribed by Jean-Marie Receveur; Emelie Bjurling; Trond Ulven; Paul Brian Little; Pia K. Nørregaard; Thomas Högberg
- Book ID
- 108073432
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 301 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0960-894X
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Melanin-concentrating hormone (MCH) is a 19-amino-acid cyclic peptide which was originally found to lighten skin color in fish that is highly conserved among many species. MCH interacts with two G-protein-coupled receptors, MCH1R and MCH2R, but only MCH1R is expressed in rodents. MCH is mainly synth
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