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4-(6-Methoxy-2-naphthyl)butan-2-one and related analogs, a novel structural class of antiinflammatory compounds

โœ Scribed by Goudie, Alexander C.; Gaster, Laramie M.; Lake, Antony W.; Rose, Carl J.; Freeman, Patricia C.; Hughes, Bryn O.; Miller, David


Book ID
120348504
Publisher
American Chemical Society
Year
1978
Tongue
English
Weight
678 KB
Volume
21
Category
Article
ISSN
0022-2623

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## Abstract The reaction of 2โ€chloroโ€4โ€(methylsulfonyl)benzoyl chloride (5) with 1โ€methylโ€1__H__โ€2,1โ€benzothiazinโ€4โ€(3__H__)โ€one 2,2โ€dioxide (4) gave the __O__โ€benzoyl compound, 1โ€methylโ€2,2โ€dioxidoโ€1__H__โ€2,1โ€benzothiazinโ€4โ€yl 2โ€chloroโ€4โ€(methylsulfonyl)benzoate (6), which rearranged to give the C