[4-3H]-labelling of the calcium ionophore A 23187 (calcimycin)

✍ Scribed by M. Prudhomme; G. Jeminet; D. Schott; J. L. Morgat; P. Beaulieu

• Book ID: 102372777
• Publisher: John Wiley and Sons
• Year: 1989
• Tongue: French
• Weight: 214 KB
• Volume: 27
• Category: Article
• ISSN: 0022-2135
• DOI: 10.1002/jlcr.2580271212

✦ Synopsis

4-3H-labelled] -A 23187 (or calcimycin) has been obtained as a magnesium salt from the corresponding 4-bromo derivative using tritiated hydrogen gas in the presence of 10% Pd/C catalyst. The specific radioactivity proved to be 50.6 Ci/mmole (1872.2 GBq/m mole).