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4-1BBL coexpression enhances HIV-specific CD8 T cell memory in a poxvirus prime-boost vaccine

✍ Scribed by Jodie M. Harrison; Edward M. Bertram; David B. Boyle; Barbara E.H. Coupar; Charani Ranasinghe; Ian A. Ramshaw

Book ID: 116959103
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 542 KB
Volume: 24
Category: Article
ISSN: 0264-410X
DOI: 10.1016/j.vaccine.2006.06.007

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## Abstract As a part of a long‐term effort to develop vaccine against HIV‐1 clade A inducing protective T cell responses in humans, we run mutually complementing studies in humans and non‐human primates (NHP) with the aim to maximize vaccine immunogenicity. The candidate vaccine under development