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3R and 4R tau isoforms in paired helical filaments in Alzheimer’s disease

✍ Scribed by Hasegawa, Masato; Watanabe, Sayuri; Kondo, Hiromi; Akiyama, Haruhiko; Mann, David M. A.; Saito, Yuko; Murayama, Shigeo


Book ID
121570542
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
319 KB
Volume
127
Category
Article
ISSN
0001-6322

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## Abstract ## Objective Olfactory dysfunction is common in Alzheimer disease (AD) and other neurodegenerative diseases. Paired helical filament (PHF)‐tau, α‐synuclein, and amyloid‐β lesions occur early and severely in cerebral regions of the olfactory system, and they have also been observed in o