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3P-0680 Histone deacetylase inhibitor (trichostatin A) inhibits vascular smooth muscle cells proliferation via upregulation of cyclin dependent kinase inhibitor p21waf1

✍ Scribed by Okamoto, H.; Taniguchi, T.; Yasuda, T.; Kamemura, K.; Ninomiya, K.; Takaishi, H.; Takahashi, A.; Ishikawa, Y.; Yokoyama, M.

Book ID: 118632288
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 61 KB
Volume: 4
Category: Article
ISSN: 1567-5688
DOI: 10.1016/s1567-5688(03)90899-3

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## Abstract Smooth muscle cells (SMC) play a central role in common vascular pathologies such as atherosclerosis and restenosis. Understanding the molecular regulation of SMC proliferation at a transcriptional level may provide important clues for the targeted control of vascular hyperplasia. We re