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[3H]TCP: a new tool with high affinity for the PCP receptor in rat brain

✍ Scribed by Jacques Vignon; Robert Chicheportiche; Michèle Chicheportiche; Jean-Marc Kamenka; Patrick Geneste; Michel Lazdunski

Book ID
118868948
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
288 KB
Volume
280
Category
Article
ISSN
0006-8993

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In vivo labeling of phencyclidine (PCP)
In vivo labeling of phencyclidine (PCP) receptors with 3H-TCP in the mouse brain
✍ T. Maurice; J. Vignon 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 774 KB

The phencyclidine (PCP) derivative N-[l-(2-thienyl) cyclohexyl]-piperidine (3H-TCP) was used to label in vivo the N-methyl-D-aspartate (NMDA) receptor-associated ionic channel in the mouse brain. After the injection of a tracer dose of 3H-TCP, a spread labeling throughout the brain was observed, but