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[3H]Dihydroergonine binding to ?-adrenergic receptors in human platelets

✍ Scribed by Jakobs, K. H. ;Rauschek, R.

Publisher
Springer-Verlag
Year
1978
Tongue
English
Weight
800 KB
Volume
56
Category
Article
ISSN
1432-1440

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✍ F. Blandini; J.T. Greenamyre πŸ“‚ Article πŸ“… 1995 πŸ› Elsevier Science 🌐 English βš– 341 KB

We have developed an assay for the binding of [3H]-dihydrorotenone ([3H]DHR), an analogue of the pesticide rotenone, to the mitochondrial enzyme, complex I, in intact human platelets. The highly hydrophobic nature of dihydrorotenone, which diffuses easily through biological membranes, rendered the i