[3H]Acetylcholine and [3H]5-hydroxytryptamine release from rat midbrain slices and the effects of calcium and phenobarbital
β Scribed by Judith A. Richter; Susan K. Jackson
- Publisher
- Springer
- Year
- 1980
- Tongue
- English
- Weight
- 654 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0364-3190
No coin nor oath required. For personal study only.
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## Abstract Hydroxylamine (0.01β30 mM), a nitric oxide (NO) generator, produced a concentrationβdependent release of [^3^H]dopamine ([^3^H]DA) from rat striatal slices. Hemoglobin (10 ΞΌM), a NO scavenger, reduced basal [^3^H]DA release and blocked hydroxylamine (100 ΞΌM)βstimulated [^3^H]DA efflux.
## Abstract Serotonin (5βHT) nerve terminals innervate sympathetic preganglionic neurons of the intermediolateral cell column (IML); however, neither the depolarizationβinduced release of 5βHT nor the presence of presynaptic modulatory autoreceptors have been directly studied in this system. We use