γ-aminobutyric acid transporter (BGT-1)
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M.-E. Ruiz-Tachiquín; E. Sánchez-Lemus; L.-E. Soria-Jasso; J.-A. Arias-Montaño;
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Article
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2002
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John Wiley and Sons
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English
⚖ 314 KB
The properties of a transport system specific for gamma-aminobutyric acid (GABA) expressed in human U373 MG astrocytoma cells were examined. The uptake of [(3)H]GABA was dependent on both extracellular Na(+) and Cl(-) ions and was inhibited by (+/-)-nipecotic acid, guvacine, and beta-alanine, with a