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3H-spiroperidol binding to two receptor sites in both the corpus striatum and frontal cortex of rat brain

โœ Scribed by N.W. Pedigo; T.D. Reisine; J.Z. Fields; H.I. Yamamura

Book ID
118322776
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
200 KB
Volume
50
Category
Article
ISSN
0014-2999

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โœ E. B. Nielsen; M. Nielsen; C. Braestrup ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› Springer ๐ŸŒ English โš– 552 KB

After 5 days of continuous treatment with d-amphetamine base in doses greater than 0.5 mg/kg/h maintained by subcutaneously implanted osmotic minipumps, specific binding of 3H-spiroperidol was reduced in rat striatum and frontal cortex as previously reported. These effects were dose-dependent at low