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[3H]-Norcocaine and [3H]-pseudococaine: Effect of N-demethylation and C2-epimerization of cocaine on its pharmacokinetics in the rat

✍ Scribed by A. L. Misra; R. B. Pontani; S. J. Mule'


Book ID
112664913
Publisher
Springer
Year
1976
Tongue
English
Weight
326 KB
Volume
32
Category
Article
ISSN
1420-682X

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## Abstract Competition by endogenous dopamine with the binding of D~2~ dopamine receptor ligands may be important in the interpretation of positron emission tomography (PET) neuroreceptor studies. PET studies with N‐methylspiperone (NMSP) have revealed increased D~2~ dopamine receptors in schizoph