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[3H]-BRL 43694 (granisetron), a specific ligand for 5-HT3 binding sites in rat brain cortical membranes

✍ Scribed by David R. Nelson; David R. Thomas

Book ID
115781014
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
396 KB
Volume
38
Category
Article
ISSN
0006-2952

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✍ Keith Miller; Ellen Weisberg; Paul W. Fletcher; DR. Milt Teitler πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 866 KB

Bovine area postrema tissue was used as a convenient source of tissue for studies of brain 5HT3 receptors. 5HT3 receptor density was determined to be 97 5 5 fmoVmg and 124 k 10 fmoVmg of protein using the commercially available 5HT3 radioligands, 3H-GR65630 and 3H-BRL43694, respectively. The equilib