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3D Structure of the Complex of MDL 63,246 with the Cell Wall Model Peptide Ac 2 -Lys- d -Ala- d -Ala

✍ Scribed by Kurz, Michael; Guba, Wolfgang; Andreini, Bianca Patrizia


Book ID
126780480
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
223 KB
Volume
118
Category
Article
ISSN
0002-7863

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N-1 and N-2 positional effects in the pr
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The N-1 Ala 2 and N-2 Gly 3 positional amino acids in the type II 0 turn templated 3 10 helix Boc-(D)Glu 1 -Ala 2 -Gly 3 -Lys 4 -NHMe (1) and Boc-(D)Glu 1 -Ala 2 -Gly 3 -Lys 4 -Ala 5 -Leu 6 -OMe (3) are substituted with Pro 2 and Ala 3 to obtain its variants Boc-(D)Glu 1 -Pro 2 -Ala 3 -Lys 4 -NHMe (