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3D-QSAR study of 20 (S)-camptothecin analogs

✍ Scribed by Ai-jun LU; Zhen-shan ZHANG; Ming-yue ZHENG; Han-jun ZOU; Xiao-min LUO; Hua-liang JIANG

Book ID
111355134
Publisher
Nature Publishing Group
Year
2007
Tongue
Chinese
Weight
490 KB
Volume
28
Category
Article
ISSN
1671-4083

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## Abstract The synthesis is given for three ring A tritiated camptothecin (CPT) analogs as biological probes in the study of the parent compounds which are of current widespread interest as potent anticancer agents. The strategy of catalytic tritolysis of aryl halide bonds was employed, and thus t