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3D-QSAR and molecular modeling of HIV-1 integrase inhibitors

✍ Scribed by Mahindra T. Makhija; Vithal M. Kulkarni

Book ID
110392933
Publisher
Springer Netherlands
Year
2002
Tongue
English
Weight
372 KB
Volume
16
Category
Article
ISSN
0920-654X

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## Abstract Human immunodeficiency virus type 1 (HIV‐1) integrase (IN) is an essential enzyme for splicing a viral DNA (vDNA) replica of its genome into host cell chromosomal DNA (hDNA) and has been recently recognized as a promising therapeutic target for developing anti‐AIDS agents. The interacti