3D pharmacophore models for thromboxane A2receptor antagonists
β Scribed by Jing Wei; Yixi Liu; Songqing Wang
- Publisher
- Springer-Verlag
- Year
- 2009
- Tongue
- English
- Weight
- 290 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1610-2940
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Because of its involvement in HIV entry, the chemokine receptor CXCR4 is an attractive target for antiretroviral drugs. Despite the large number of CXCR4 inhibitors studied, the 3D pharmacophore for binding to CXCR4 remains elusive, mainly as a result of conformational flexibility inher
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Synthesis, Structural Characterization and Thromboxane A 2 Receptor Antagonistic Activity of 3-Substituted 2-[(Arylsulfonyl)imino]-2,3-dihydrothiazolyl Derivatives. -Seven new title derivatives such as (I) are prepared by the Hantzsch synthesis. Compounds (I) show significant binding affinities in