387 Gene expression array, phenotypic, and functional assessment of human dendritic cells engulfing HCV-infected apoptotic cells

Engulfment of apoptotic cells expressing

Engulfment of apoptotic cells expressing HCV proteins leads to differential chemokine expression and STAT signaling in human dendritic cells

✍ Anne M. Wertheimer; Stephen J. Polyak; Rachel Leistikow; Hugo R. Rosen 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 939 KB

In the majority of cases, infection with hepatitis C virus (HCV) becomes chronic and is often associated with impaired innate and adaptive immune responses. The mechanisms underlying viral persistence and lack of protective immunity are poorly understood. Considering that dendritic cells (DCs) play