𝔖 Bobbio Scriptorium
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3.7 Molecular alterations in oncogenes or tumor suppressor genes during chemical carcinogenesis

✍ Scribed by Burns, P.A.; Brown, K.; Bremner, R.; Clarke, M.; Balmain, A.


Book ID
122529940
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
535 KB
Volume
23
Category
Article
ISSN
0079-6336

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On a genetic level, renal-cell carcinoma has been characterized by an abnormality on the short arm of chromosome 3 (3p), which suggests the inactivation of a tumor suppressor gene. One tumor suppressor gene at 3p, the von Hippel-Lindau disease gene, is implicated in tumor development of a whole spec