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365 ANALYSIS OF REGULATORY T CELLS IN PATIENTS AFFECTED BY RENAL CELL CARCINOMA

✍ Scribed by Traverso, Paolo; Filaci, Gilberto; Varca, Virginia; Fenoglio, Daniela; De Rose, Aldo Franco; Carmignani, Giorgio

Book ID
123013206
Publisher
Lippincott Williams and Wilkins
Year
2010
Tongue
English
Weight
51 KB
Volume
183
Category
Article
ISSN
0022-5347

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## Abstract Tyrosine kinase inhibitors (TKIs) as sorafenib are known to reduce the number of immunosuppressive regulatory T cells (Tregs) in the peripheral blood and thereby shifting the immune balance to a more stimulating setting. The effect of sorafenib on intratumoural Tregs is unclear but impo