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351 POSTER Activity of the histone deacetylase (HDAC) inhibitor PXD101 in preclinical prostate cancer studies

โœ Scribed by M. Jeffers; X. Qian; E. Mills; W. LaRochelle; H. Lichenstein; G. Ara


Book ID
118623979
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
54 KB
Volume
4
Category
Article
ISSN
1359-6349

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Activity of the histone deacetylase inhi
โœ Xiaozhong Qian; Gulshan Ara; Evan Mills; William J. LaRochelle; Henri S. Lichens ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 751 KB

## Abstract Histone deacetylase inhibitors (HDACi) represent a promising new class of anticancer agents. In the current investigation, we examined the activity of the HDACi belinostat in preclinical models of prostate cancer. __In vitro__ proliferation assays demonstrated that belinostat potently i