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35 Increased mitochondrial biogenesis as therapy for mitochondrial myopathies

✍ Scribed by Tina Wenz; Francisca Diaz; Dayami Herandez; Bruce M. Spiegelman; Carlos T. Moraes


Book ID
116751947
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
46 KB
Volume
10
Category
Article
ISSN
1567-7249

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Clevudine (Revovir), a pyrimidine nucleoside analogue, is a recently introduced antiviral drug. Clinical trials have demonstrated potent, sustained antiviral activity against hepatitis B virus without specific adverse events. The lack of cytotoxicity and absence of an effect on mitochondrial functio