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3,5-Disubstituted 1,2,4-triazoles, a new class of xanthine oxidase inhibitor

✍ Scribed by Duggan, D. E.; Noll, R. M.; Baer, J. E.; Novello, F. C.; Baldwin, J. J.


Book ID
120181144
Publisher
American Chemical Society
Year
1975
Tongue
English
Weight
700 KB
Volume
18
Category
Article
ISSN
0022-2623

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A number of symmetrically 3,5-disubstituted 4-amino-1,2,4-triazoles have been prepared by the reaction of aromatic nitriles with hydrazine dihydrochloride or sulfate with an excess of hydrazine hydrate in ethylene or diethylene glycol under a nitrogen atmosphere. The structures of the new triazoles