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34LBA Activated cPLA2a correlates with HER2 over-expression and mediates estrogen-induced cell growth of breast cancer cells

✍ Scribed by F. Caiazza; A. Hill; L. Young; B.J. Harvey; W. Thomas

Book ID: 119600811
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 65 KB
Volume: 7
Category: Article
ISSN: 1359-6349
DOI: 10.1016/s1359-6349(09)72069-5

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## Abstract Her‐2/__neu__ (__erb__B‐2) oncogene overexpression is associated with increased tumor progression and metastasis. Fatty acid synthase (FAS), the key lipogenic enzyme responsible for the endogenous synthesis of fatty acids, has been shown to be one of the genes regulated by Her‐2/__neu__