3,4,9,9a-Tetrahydro-1,4-ethano-3,4a-(iminoethano)-4aH-carbazol-2(1H)-one derivatives. 2. Unusual results from Eschweiler-Clarke methylation
β Scribed by Bobowski, George
- Book ID
- 127202141
- Publisher
- American Chemical Society
- Year
- 1985
- Tongue
- English
- Weight
- 411 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
The carbazole unit of the title molecule, C 15 H 15 NO 3 , is not planar. The dihedral angle between the benzene ring and the fused pyrrole ring is 0.9 (1) . The cyclohexene ring is in a halfchair form. The ester group has an equatorial orientation. In the crystal structure, the molecules are stabil
The reaction of 4a-methyl-l,2,3,4-tetrahydrocarbazole (1) with organolithium reagents affords the sterically hindered alkyl, aryl or alkenyl cis-4a-methyl-9a-substituted-l,2,3,4,4a,9ahexahydrocarbazole derivatives (2) in excellent yields. Two diastereomeric pairs were isolated for the 9a-see-butyl d