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344 Hormonal regulation of tPA and PAI-1 gene expression in rat hepatocytes

✍ Scribed by Heaton, J.H.; Nebes, V.L.; O'Dell, L.G.; Morris, S.M.; Gelehrter, T.D.

Book ID
123469920
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
94 KB
Volume
2
Category
Article
ISSN
0268-9499

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## Abstract Obesity is characterized by elevated levels of circulating plasminogen activator inhibitor‐1 (PAI‐1), which contribute towards the development of secondary disorders such as type 2 diabetes mellitus and cardiovascular complications. This increase in plasma PAI‐1 levels is attributed to