Metabolic stress in PC12 cells induces t
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I. Lamensdorf; G. Eisenhofer; J. Harvey-White; Y. Hayakawa; K. Kirk; I.J. Kopin
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Article
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2000
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John Wiley and Sons
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English
โ 129 KB
๐ 1 views
3,4-Dihydroxyphenylacetaldehyde (DOPAL) has been reported to be a toxic metabolite formed by the oxidativedeamination of dopamine (DA) catalyzed by monoamine oxidase. This aldehyde is either oxidized to 3,4dihydroxyphenylacetic acid (DOPAC) by aldehyde dehydrogenase, an NAD-dependent enzyme or reduc