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3,4-Dihydro-2(1 H )-quinolinone as a Novel Antidepressant Drug: Synthesis and Pharmacology of 1-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-3,4- dihydro-5-methoxy-2(1 H )-quinolinone and Its Derivatives

✍ Scribed by Oshiro, Yasuo; Sakurai, Yoji; Sato, Seiji; Kurahashi, Nobuyuki; Tanaka, Tatsuyoshi; Kikuchi, Tetsuro; Tottori, Katsura; Uwahodo, Yasufumi; Miwa, Takashi; Nishi, Takao

Book ID
120557475
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
169 KB
Volume
43
Category
Article
ISSN
0022-2623

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πŸ“œ SIMILAR VOLUMES

ChemInform Abstract: 3,4-Dihydro-2(1H)-q
ChemInform Abstract: 3,4-Dihydro-2(1H)-quinolinone as a Novel Antidepressant Drug: Synthesis and Pharmacology of 1-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl] -3,4-dihydro-5-methoxy-2(1H)-quinolinone and Its Derivatives.
✍ Yasuo Oshiro; Yoji Sakurai; Seiji Sato; Nobuyuki Kurahashi; Tatsuyoshi Tanaka; T πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 35 KB πŸ‘ 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

5-{2-[4-(2-Methyl-5-quinolinyl)-1-pipera
5-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}-2(1H)-quinolinones and 3,4-dihydro-2(1H)-quinolinones: Dual-acting 5-HT1 receptor antagonists and serotonin reuptake inhibitors. Part 3
✍ Steven M. Bromidge; Roberto Arban; Barbara Bertani; Manuela Borriello; Anna-Mari πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 642 KB

5-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}-2(1H)-quinolinones and 3,4-dihydro-2(1H)-quinolinones have been identified with different combinations of 5-HT 1 autoreceptor antagonist and hSerT potencies and excellent rat PK profiles. The availability of tool compounds with a range of profiles