Michael Addition versus 1,3-Cycloadditio
✍
Risitano, Francesco ;Grassi, Giovanni ;Bruno, Giuseppe ;Nicolò, Francesco
📂
Article
📅
1997
🏛
John Wiley and Sons
🌐
English
⚖ 489 KB
## Abstract The reactions of (arylmethylene)isoxazol‐5‐ones 1 with pyridinium ylides 2 lead to the diastereoselective formation of olates 4. The reasons for the favored Michael addition and the unsuccessful subsequent cyclization to fused O‐heterocycles are discussed on the basis of X‐ray analysis