33A Assessment of the variation of treatment effect over time: An example in hypertension treatment
β Scribed by Florent Boutitie; Francois Gueyffier; Stuart Pocock; Jean-Pierre Boissel; INDANA Project Steering Committee
- Book ID
- 113297999
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 51 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0197-2456
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Exploration of the variation of treatment effect over time in randomized clinical trials with low event rates is limited by lack of power. A meta-analysis on individual patient data from such trials can partly solve the problem, but brings other computational difficulties. Using an example in hypert